| Player | Goals |
| Dixie Dean | 383 |
| Graeme Sharp | 159 |
| Bob Latchford | 138 |
| Sandy Young | 125 |
| Joe Royle | 119 |
| Dave Hickson | 111 |
| Roy Vernon | 111 |
| Edgar Chadwick | 109 |
| Tony Cottee | 99 |
| Kevin Sheedy | 97 |
| Alfred Milward | 97 |
| Jimmy Settle | 97 |
| Adrian Heath | 94 |
| Alex Stevenson | 90 |
| Alex Young | 89 |
| John Parker | 89 |
| Fred Geary | 86 |
| Derek Temple | 84 |
| Tommy Eglington | 82 |
| Jack Sharp | 80 |
| Jack Taylor | 80 |
| Alan Ball | 79 |
| Eddie Wainwright | 76 |
| Jimmy Cunliffe | 76 |
| Jimmy Harris | 72 |
| Duncan Ferguson | 72 |
| Bobby Parker | 71 |
| Fred Pickering | 70 |
| Alex Latta | 70 |
| Tommy Lawton | 70 |
| John Bell | 70 |
| Tim Cahill | 68 |
| Andy King | 67 |
| Bertie Freeman | 67 |
| Tommy White | 66 |
| Tommy Johnson | 65 |
| Jimmy Stein | 65 |
| Romelu Lukaku | 61 |
| Mick Lyons | 59 |
| Trevor Steven | 59 |
| Leon Osman | 58 |
| Bobby Irvine | 57 |
| Wilf Chadwick | 55 |
| Jimmy Husband | 55 |
| Wally Fielding | 54 |
| Kevin Campbell | 51 |
| Johnny Morrissey | 50 |
| Jimmy Dunn | 49 |
| Bobby Collins | 48 |
| Torry Gillick | 44 |